Linezolid Tablets Ip 600mg

Linezolid tablets IP 600 mg are powerful antibiotics meant for use in severe bacterial infections  such as infections with gram-positive bacteria resistant to other drugs. These belong to the oxazolidinone class and are highly effective against pneumonia, skin, and soft tissue infections, including drug-resistant strains like MRSA strains and VRE (Vancomycin-resistant Enterococci).

Linezolid tablet contains 600 mg of this semi-synthetic antibacterial agent with bacteriostatic (growth inhibiting) and bactericidal (bacteria killing) activities depending upon the organism and the source of the infection. Taken under medical supervision, the drug for oral use usually is given one tablet every 12 hours.

Mechanism of Action

Linezolid acts on bacterial protein synthesis. It stops the formation of the 70S initiation complex by attaching to the 50S ribosomal subunit of bacteria. Being a new mechanism of action, it prevents bacteria from further growth and reproduction and finally kills the infection. This unique mechanism makes Linezolid work in cases where other antibiotics have failed.

Uses

• Complicated and uncomplicated skin and soft-tissue infections
• Infections caused by multidrug-resistant Gram-positive bacteria
• MRSA and VRE infection
• Diabetic foot infection (without bone involvement)

Side Effects

1. Headache
2. Nausea or vomiting
3. Diarrhea
4. Dizziness
5. Anemia or low blood cell counts (long-term use)
6. Peripheral neuropathy or optic nerve damage (rare with extended use)
7. Lactic acidosis (rare)

Tips for Taking Linezolid

• Use this medicine as your doctor prescribed.
• It can be taken with or without food.
• Never skip a dose or stop early, even if you feel better.
• Avoid consuming large amounts of tyramine-containing foods (e.g., aged cheese, soy sauce, fermented products).
• Tell your doctor about any other medicines you are taking, especially antidepressants.
• Have tablets after every interval of 12 hours with or without food.
• The whole course of therapy should be completed even when symptom improvement occurs early.
• Avoid alcohol and foods rich in tyramine (e.g., aged cheese, fermented foods) that can cause a sudden rise in blood pressure.
• Never take medicines without a prescription or share your medicine with others.
• Inform your doctor about taking antidepressant medications or serotonergic drugs.

Storage Instructions

1. Store in a cool, dry place below 25°C.
2. Protect from moisture and direct sunlight.
3. Keep out of reach of children.
4. Do not use if the package is damaged or after the expiry date.