Pregabalin (SR), Mecobalamin & Nortriptyline Tablets

Pregabalin (SR), Mecobalamin & Nortriptyline Tablets

Pexaglin-MNT – Pregabalin + Nortriptyline + Mecobalamin is a combination of three medications: pregabalin, nortriptyline, and mecobalamin. Pregabalin is an alpha-2 delta ligand that relieves pain by altering the calcium channel activity of nerve cells. Nortriptyline is a tricyclic antidepressant that raises the levels of chemical messengers (serotonin and noradrenaline), which inhibit the movement of pain signals in the brain. Mecobalamin is a type of vitamin B that aids in the development of myelin, a material that protects nerve fibers and rejuvenates damaged nerve cells. The combination of these medications relieves neuropathic pain.

Uses of this medication

• The combination of these medications is used to treat neuropathic pain.

Medicinal Benefits of this medication

Mecobalamin+nortriptyline+pregabalin is a combination of three drugs: mecobalamin (vitamin B), nortriptyline (an antidepressant), and pregabalin (an anticonvulsant). The combination of mecobalamin, nortriptyline, and pregabalin is used to treat neuropathic pain caused by diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, and other conditions. Methylcobalamin helps to produce myelin, a material that protects nerve fibers and regenerates injured nerve cells. Nortriptyline works by boosting nerve transmitters (serotonin and noradrenaline) in the brain, which reduces the number of pain messages that reach the brain. Pregabalin relieves pain by interfering with pain messages that go through the brain and down the spine. Methylcobalamin, nortriptyline, and pregabalin assist relieve neuropathic pain.

Side Effects of this medication

Pregabalin (SR), Mecobalamin & Nortriptyline Tablets, like other drugs, can have certain negative side effects. However, these side effects do not require medical treatment and will go away once your body responds to the medication. Consult your doctor if you continue to encounter these side effects and seek medical attention.

• Constipation
• Dry mouth
• Headache
• Feeling sleepy, tired, or dizzy
• Diarrhea

How to take this medication

Take this medication as advised by your doctor, to get better results take this medication with dose and duration. Do not chew or crush this medication, swallow it as a whole with a glass of water. 

How this medication works

Methylcobalamin (vitamin), nortriptyline (antidepressant), and pregabalin (anticonvulsant). Methylcobalamin is a vitamin that helps produce myelin, which protects nerve fibers and regenerates injured nerve cells. Nortriptyline works by boosting nerve transmitters (serotonin and noradrenaline) in the brain, which reduces the number of pain messages that reach the brain. Pregabalin relieves pain by interfering with pain messages that go through the brain and down the spine. The combination of methylcobalamin, nortriptyline, and pregabalin is effective in treating neuropathic pain.

Storage of this medication.

• Store this medication in a cool and dry place away from direct heat and sunlight.
• Keep this medication away from the reach of your children and pets.

Precautions for taking this medication

Alcohol – Avoid the consumption of alcohol while taking this medication.

Pregnancy – If you are pregnant or planning to conceive then never take this medication without consulting with your doctor. Your doctor will only prescribe this medication if the benefits outweigh the risks.

Breastfeeding – If you are nursing your child then never take this medication without consulting with your doctor. There is no substantial research yet on the use of this medication in breastfeeding.

Driving – Do not drive after taking this medication, it may decrease the alertness and ability of driving. This medication may cause drowsiness and blurred vision. So, do not drive or operate machinery unless you are alert.

Liver – Dosage adjustment may needed for this medication, if you are suffering from liver disease then consult with your doctor before taking this medication. Your doctor may prescribe this medication with some caution.

Kidney – If you are suffering from kidney impairment then never take this medication without consulting with your doctor. If you have kidney impairment of any concerns with your doctor, they will prescribe this medication only if the benefits are more than the risks.