Pregabalin and Duloxetine (Delayed Release) Capsules

PEXAGLIN D 20, is a Capsule that helps to treat neurological and mood problems. It’s a combination of two powerful ingredients: Pregabalin and Duloxetine Pregabalin reduces pain signals in the brain, while Duloxetine improves mood and eases feelings of sadness and anxiety. This tablet not only helps with nerve pain but also makes people feel better emotionally, leading to a happier life.

PEXAGLIN D 20 is made to work well and be safe for people. The Duloxetine in it is released slowly to avoid strong side effects. Whether someone has long-lasting pain from nerve issues or feels really down and anxious, this is the best Capsule to get relief.

Key Ingredients of Pregabalin and Duloxetine (Delayed Release) Capsules

This Capsule is made with two main & active ingredients that are: Pregabalin & Duloxetine. Let’s see the working of both ingredients:

Pregabalin

The Pregabalin ingredients belong to a neuropathic pain agent that works by modulating the calcium channels, which release the neurotransmitter to provide relief to nerve pain & seizures. Here are some benefits of Pregabalin:

• Improve sleep quality
• Effective treatment for neuropathic pain
• Reduceorry & tension
• Rapid onset of action
• Fewer drug interactions

Duloxetine

The Duloxetine ingredient comes from the group of SNRI, which is well known for improving the mood by increasing the level of serotonin in the brain. With the increasing level, the mind starts improving the mood and also provides relief from the pain signals. Some benefits of Duloxetine are:

• Dual action on pain & mood
• Reduce Neuropathic pain
• Reduce anxiety
• Enhance sleep quality
• Non-habit forming
• Suitable for long-term management

Common Inactive Ingredients

Some common inactive ingredients in Pregabalin & Duloxetine capsules are:

• Microcrystalline Cellulose
• Lactose Monohydrates
• Magnesium Stearate
• Gelatin
• Sodium starch glycolate
• Titanium Dioxide

How to use:

Take the Capsule as prescribed by your doctor, with water.

• To reduce stomach upset, take PEXAGLIN D 20 with meals.
• Don’t crush or chew the tablet; swallow it whole.
• Limit or avoid alcohol while using this tablet.
• Take it at the same time daily for the best results
• If you miss one, take it when you remember, but don’t double the dose.
• Let your doctor know about other medications or allergies.

Benefits of Pregabalin and Duloxetine (Delayed Release) Capsules:

Pregabalin and Duloxetine have many benefits and can greatly help people with neurological and mood-related difficulties enhance their lives. Here are some important benefits of this tablet:

Effective Pain Relief: PEXAGLIN D 20 contains Pregabalin, which targets nerve-related pain effectively. It helps reduce discomfort caused by conditions like neuropathy and fibromyalgia, allowing individuals to experience relief and better manage their daily activities.

Mood Enhancement:It helps with both physical pain and emotional well-being. It makes you feel happier and less sad or anxious when you have conditions like major depressive disorder and generalized anxiety disorder.

Comprehensive Treatment:By combining Pregabalin and Duloxetine, this tablet offers a comprehensive approach to managing both physical and emotional symptoms. It provides a holistic solution for individuals dealing with complex conditions that involve both pain and mood disturbances.

Gradual Release: PEXAGLIN D 20’s delayed-release formulation of Duloxetine ensures a controlled and gradual release of the drug in the body. This minimises the risk of strong side effects and improves patient comfort and compliance.

Side effects:

Like any medication, it may also have potential side effects. It’s important to be aware of these possible adverse reactions. Here are some common side effects associated with PEXAGLIN D 20:

• Nausea
• Dizziness
• Drowsiness
• Dry mouth
• Constipation
• Weight changes
• Headache
• Blurred vision
• Increased sweating<
• Anxiety
• Sleep problems

Precautions:

• Follow your doctor’s advice.
• Inform about allergies and medical history.
• Discuss other medications with your doctor.
• Consult your doctor if you are pregnant or breastfeeding.
• Limit alcohol consumption.
• Be cautious while driving or using machinery.
• Elderly individuals should take extra care.
• Don’t stop abruptly without a doctor’s advice.
• Seek medical help if you suspect an overdose.

Storage Information

For storing this capsule, you should consider the following things:

1. Keep between15°C to 25°C ( Room Temperature)
2. Keep the capsule in the original bottle or blister
3. Stay restricted with children
4. Avoid flushing or freezing the capsules

Warnings:

Interaction with Drugs

• Antidepressant medicines
• Moclobemide,
• Paroxetine,
• Fluoxetine
• Venlafaxine,
• Clomipramine,
• Amitriptyline
• Antibiotic Medicines
• Linezolid
• Tramadol

Interaction with food – No interaction

Interaction with Beverages – Avoid Alcohol

Interaction with Diseases

People having diseases like should avoid this medicine:

• Heart problems
• Glaucoma
• Drug abuse
• Suicidal tendencies
• Alcoholism

Habit Forming – Yes

Lifestyle

• Exercise regularly
• Rest well
• Sleep on time
• Avoid smoking
• Meditation and Yoga can help

FAQs about Pexaglin D 20

Ques: How does PEXAGLIN D 20 work?

Ans: Pregabalin and Duloxetine are two types of medications. Pregabalin helps relieve pain caused by nerves by affecting certain channels in nerve cells that involve calcium. On the other hand, Duloxetine boosts the levels of serotonin and norepinephrine, which can improve your mood and make you feel less sad and anxious.

Ques: Can I take Pregabalin and Duloxetine with other medications?

Ans: Before starting Pregabalin and Duloxetine, inform your doctor about all the medications, supplements, or herbs you are taking. Some drugs may interact with Pregabalin and Duloxetine, so it’s important to discuss this with your healthcare provider.

Ques: What should I do if I miss a dose of Pregabalin and Duloxetine?

Ans: If you forget to take a dose, take it as soon as you remember, unless it’s close to the time for the next dose. Never take a double dose to make up for a missed one.

Ques. Can People get addicted to these capsules?

Answer: As you know, misuse of any medicine can be harmful. With this medication, this capsule can be addictive if you misuse the dose. Take the medicine with a strict prescription.

Ques: Can I stop these Capsules while my symptoms are normal?

Never stop taking these capsules, as it may cause withdrawal symptoms, which may be worse. Always consult your healthcare provider first.

Ques: How much time does it take to act on patients?

It takes time to show full effects, and it depends on the person; some show improvement in the first week, so you should use it as prescribed by your doctor.

Composition	Each Hard Gelatin Capsule Contains:- Pregabalin–75 mg Duloxetine –20 mg (as delayed release Pellets)
Packing Size	6*10 Alu Alu