Top 10 Gliclazide and Metformin Tablets in India:- Gliclazide + Metformin is a mixture of two anti-diabetic drugs: Gliclazide and Metformin. Gliclazide is a ‘sulfonylurea’ which works by increasing the number of insulin formulated by the pancreas. Metformin, which is a ‘biguanide’, helps by decreasing the glucose formation in the liver, delaying glucose absorption from the intestines, and increasing the body’s response to insulin. In a nutshell, the two medicines stop blood glucose levels from increasing to very high levels, thus maintaining your Diabetes under control. Gliclazide and Metformin work together to control your blood sugar levels under check. The strict control of blood sugars is mainly important to mention the many disabling side effects of Diabetes.