Sitagliptin and dapagliflozin are two different medications used to treat type 2 diabetes. They are sometimes combined into a single tablet for convenience.
When combined into a single tablet, sitagliptin and dapagliflozin provide dual mechanisms of action to improve glycemic control in patients with type 2 diabetes. This combination can help lower blood sugar levels after meals, increase insulin production, reduce glucose production by the liver, promote urinary excretion of glucose, and potentially lead to weight loss.
Sitagliptin: Sitagliptin is a type of medicine that is part of a group of drugs called DPP-4 inhibitors. It works by inhibiting the action of the DPP-4 enzyme, which helps regulate blood sugar levels. By inhibiting this enzyme, sitagliptin increases the levels of incretin hormones in the body. Incretins stimulate the pancreas to produce more insulin when blood sugar levels are high and reduce the production of glucose by the liver. This helps reduce sugar levels in the blood after eating.
Dapagliflozin: Dapagliflozin is a medication classified as a sodium-glucose co-transporter 2 (SGLT2) inhibitor. SGLT2 inhibitors work by blocking the reabsorption of glucose by the kidneys, leading to increased urinary excretion of glucose. This process helps reduce high levels of sugar in the blood by getting rid of extra sugar through urine. Dapagliflozin also promotes weight loss and may have positive effects on blood pressure and cardiovascular health.
To treat type 2 diabetes, you can use Sitagliptin and Dapagliflozin tablets.
Sitagliptin & Dapagliflozin Tablets may offer several potential benefits. Here are some possible benefits associated with Sitagliptin & Dapagliflozin Tablets:
Lowering blood glucose levels: Both Sitagliptin and Dapagliflozin may help to lower blood glucose levels by reducing the amount of glucose produced by the liver and increasing urinary glucose excretion respectively.
Improved insulin resistance: Sitagliptin & Dapagliflozin tablets may help improve insulin resistance, a common issue associated with diabetes.
Weight management: Dapagliflozin may help reduce body weight, particularly in combination with Sitagliptin.
Fewer side effects: Using Sitagliptin & Dapagliflozin tablets in combination may produce fewer side effects than using either medication alone.
Improved cardiometabolic risk factors: Dapagliflozin may be more effective than Sitagliptin at improving certain cardiometabolic risk factors, such as lipid levels.
Here are some potential side effects of using Sitagliptin & Dapagliflozin tablets:
Hypoglycemia (low blood sugar) – The medication may lower blood sugar levels leading to symptoms such as sweating, shakiness, confusion, and dizziness.
Urinary tract infections – Symptoms may include painful urination, frequent urination, and urgency.
Genital yeast infections – Symptoms may include itching, burning, and discharge.
Hypotension (low blood pressure) – Dapagliflozin may cause a drop in blood pressure, leading to symptoms such as dizziness, lightheadedness, and fainting.
Gastrointestinal distress – The medication may cause an upset stomach, diarrhea, and abdominal pain.
Headache – Some individuals may experience headaches while using Sitagliptin & Dapagliflozin tablets.
Here are some general precautions associated with sitagliptin and dapagliflozin:
Sitagliptin & Dapagliflozin Tablets